Best selles drugs with estradiol
| Prodcuts | Price | |
| Climara-50 (Estradiol) | 50 tablets/28$ |
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| Climen (Cyproterone acetate and Estradiol valerate) | 21 tablets/28$ |
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| Klimodien (dienogest and estradiol valerat) | 28 tablets/34$ |
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| Oestrogel (Estradiol) | 1 tube (0.06%) 28$ |
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| Pausogest (Estradiol and Norethisterone) | 28 tablets /25$ |
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| Diane-35 | 21 tablets/27$ |
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| Femoden (ethinyloestradiol and gestodene) | 21 tablets/24 |
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| Yasmin | 21 tablets/28$ |
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| Microgynon (Levonorgestrel and Ethinylestradiol) | 21 tablets/13$ |
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Estradiol. Estradiol level
What is estradiol (E2, Estradiol)?
This is the most active estrogen (female) sex steroid hormones.
From the viewpoint of biosynthesis - estradiol is a derivative of cholesterol, and its immediate predecessors are androstenedione and testosterone. For women, it is produced in the ovaries, the placenta and the adrenal cortex under the influence of follicle-stimulating hormone (FLG), luteinizing hormone (LH) and prolactin. In small quantities, estradiol is produced in the conversion of testosterone. Ensures the formation of estradiol in the female sexual system type, the development of female secondary sexual characteristics in the adolescent period, the regulation of the menstrual cycle, the ovule development, growth and development of the uterus during pregnancy, is responsible for the physiological peculiarities of sexual behavior, ensures the formation of subcutaneous adipose tissue of the female type. The main action - is an enhanced growth of cells lining inside the uterus that prepares her for pregnancy, and reducing the resistance of the uterine vessels, increases in blood flow. For women of childbearing age, the level of estradiol in serum and blood plasma depends on the phase of the menstrual cycle. At the beginning of the cycle the concentration of estradiol is slowly increasing. The highest levels of estradiol
observed in the late follicular phase - before ovulation. Ovulation (follicle breaking and entering the ovule) occurs after 24-36 hours after the estradiol concentration reaches its maximum level. After ovulation hormone level starts to drop, but during the luteal phase, it rises again. If conception has not occurred, the level of estradiol falls to a minimum, which defines the beginning of menstruation. If conception occurred, the concentration of estradiol continued to increase.
During pregnancy the concentration of estradiol in the blood increases at the time of delivery, and after giving birth, she returned to normal at the 4 th day. With increasing age in women, the decrease of the concentration of estradiol. In postmenopause concentration of estradiol is reduced to very low values. As is normal for women most of the estradiol is synthesized in the ovaries, the analysis of its concentration can be considered a way to assess ovarian function. In addition, the level of estradiol is used in the survey with amenorrhea, premature sexual development, infertility in men and women, to assess the early menopause. Monitoring the concentration of estradiol is necessary in preparation for fertilization in vitro, because the extraction of ovules held at a certain stage of follicle development, which depends on the concentration of estradiol.
Among men, estradiol is formed in the testes, the adrenal cortex, but most - in the peripheral tissues through the conversion of testosterone.
Estradiol has anabolic effects, enhances the exchange of bone tissue and accelerates the growth of long bones. Contributing to the delay of sodium and water in the body. Lowers cholesterol and increases the activity of the blood that is Sverre. Estradiol improves nervous tension, irritability.
Daily fluctuations of concentration of estradiol in the serum associated with the rhythm of secretion of luteinizing hormone (LH): a maximum of accounts for the period from 15 to 18 hours, at least - between 24 and 2 pm
Preparing to study: lack of physical activity, smoking, women produce a study on the 6-7 day of menstrual cycle.
Deadline: 1 working day.
When the estradiol level increased?
Estradiol level increased - Follicles persistence; Estradiol level increased -Endometrioid ovarian cysts; Estradiol level increased -Secretore Hormone ovarian tumor; Estrogen secreting a swelling of testicles; Estradiol level increased -Cirrhosis of the liver.
Receiving drugs (anabolic steroids, carbamazepine, tsimetidin-men and women in postmenopausal, klomifen - in postmenopausal women, ketokonazol - at hipper androgenic women mifepristone - in patients with meningiomas, nafarelin - with subcutaneous injection polikistoza ovarian syndrome, phenytoin, tamoxifen, troleandomitsin, valproevaya acid; estrogen - oral contraceptives).
When the level of estradiol is reduced?
estradiol level is reduced - The intensive physical activity at non train women; estradiol level is reduced -A considerable loss of weight; estradiol level is reduced -Diet high in carbohydrates and low in fat, the vegetarians; estradiol level is reduced -Smoking; estradiol level is reduced -Pregnancy at an early stage; estradiol level is reduced -Turner's syndrome; estradiol level is reduced -Testicular feminization; estradiol level is reduced -Hypogonadism; estradiol level is reduced -Hyperprolactinemia; estradiol level is reduced -hypophysial nanism; estradiol level is reduced -Inadequate lutein phase; estradiol level is reduced -Virilism; estradiol level is reduced -Chronic inflammation of internal genital organs; estradiol level is reduced -The threat of termination of pregnancy endocrine genesis; estradiol level is reduced -Chronic prostatitis.
Estradiol level is treated by Receiving drugs (Climara-50 (Estradiol), Climen (Cyproterone acetate and Estradiol valerate) , Klimodien (dienogest and estradiol valerat) , Oestrogel (Estradiol), Pausogest (Estradiol and Norethisterone),Diane-35 (cyproterone acetate and ethinyl estradiol), Femoden (ethinyloestradiol and gestodene),Jeanine (Ethinylestradiol and Dienogest), Microgynon (Levonorgestrel and Ethinylestradiol)).
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